Albendazole 400mg tablet is a widely used antiparasitic medication designed to treat various intestinal worm infections in both adults and children. Belonging to the benzimidazole class of anthelmintics, this tablet is effective in eliminating parasitic worms from the digestive tract by inhibiting their ability to absorb glucose, which eventually causes their death. This makes Albendazole a vital part of global deworming programs and routine parasite treatment strategies. Buy Albendazole 400 Mg Online at top pharmacy Medzsupplier.
How Does Albendazole Works?
Albendazole works by disrupting the microtubule structure within the cells of intestinal parasites. This interference impairs the parasite’s ability to uptake glucose, leading to a depletion of energy reserves. As a result, the worms become immobile and are eventually expelled from the body through natural bowel movements. The drug is particularly effective against common worms such as roundworms (Ascaris lumbricoides), hookworms (Ancylostoma duodenale and Necator americanus), whipworms (Trichuris trichiura), and pinworms (Enterobius vermicularis).
Indications for Use
The 400mg dose of Albendazole is typically used as a single-dose treatment in mass deworming campaigns, especially in regions where intestinal worms are endemic. It is effective for:
Ascariasis
Enterobiasis
Trichuriasis
Ancylostomiasis
Strongyloidiasis
Taeniasis
Giardiasis
In some cases, Albendazole is also used as part of combination therapy for hydatid disease (caused by Echinococcus granulosus) and neurocysticercosis (caused by Taenia solium larvae in the brain).
Dosage and Administration
For treating most intestinal parasitic infections, a single 400mg dose of Albendazole is sufficient. It can be taken with or without food, but a fatty meal may improve absorption, particularly when treating tissue infections. In children, the same 400mg dose is often used for those above two years of age. For children aged 1–2 years, the usual dose is 200mg. However, dosage may vary depending on the severity of the infection and the patient's medical condition, so a healthcare provider should always be consulted before use.
For hydatid disease or neurocysticercosis, longer treatment durations and multiple doses may be prescribed under close medical supervision.
Safety and Side Effects
Albendazole Tablet is generally well-tolerated. Most people do not experience significant side effects when taking a single 400mg dose. However, some may encounter mild gastrointestinal symptoms such as:
Nausea
Abdominal pain
Diarrhea
Headache
Dizziness
For patients on prolonged treatment (e.g., for cysticercosis), rare but more serious side effects can occur, including elevated liver enzymes, bone marrow suppression, or allergic reactions. Routine blood and liver function tests may be necessary during long-term therapy.
Albendazole should not be used during pregnancy unless clearly needed, especially in the first trimester. It is recommended to use effective contraception while on this medication and for a month after completing treatment. Breastfeeding mothers should consult a doctor before taking the drug.
Benefits of Albendazole
Albendazole’s effectiveness, affordability, and wide availability have made it a first-line treatment in global parasite control programs. It plays a critical role in reducing worm burden, improving nutritional outcomes, and supporting cognitive and physical development in children, especially in areas where hygiene and sanitation are limited. It is endorsed by the World Health Organization (WHO) and other public health bodies for mass deworming campaigns.
Availability
Albendazole 400mg tablets are available under various brand names worldwide, including Zentel, Alworm, and Eskazole. It can be obtained over the counter in many countries or prescribed by healthcare professionals. In India, it is widely distributed in pharmacies, clinics, and government-run health initiatives.
Conclusion
Albendazole 400mg tablet is a safe, effective, and widely used medication for treating intestinal worm infections. It offers fast relief from common parasitic worms such as roundworms, hookworms, and pinworms, while also serving as an essential tool in global efforts to eliminate parasitic diseases. By using Albendazole under proper medical guidance, individuals and communities can significantly reduce the burden of worm infections and improve overall public health.